Yakuchinone B CAS NO.81840-57-5

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

Yakuchinone B exerts its biological effects primarily through the inhibition of key inflammatory mediators. It has been shown to suppress the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) by attenuating the activation of the transcription factor NF-κB. Additionally, it functions as a potent antioxidant by scavenging reactive oxygen species (ROS), reducing oxidative stress, and enhancing the activity of endogenous antioxidant enzymes like superoxide dismutase (SOD) and catalase (CAT), thereby protecting cells from apoptosis and damage.

2.PRODUCT INDICATIONS

Yakuchinone B is indicated for applications related to neuroprotection, anti-inflammatory therapy, and metabolic health. It is particularly beneficial for individuals seeking natural support for cognitive function and those managing conditions associated with oxidative stress, such as neurodegenerative disorders. Its ability to inhibit islet amyloid polypeptide aggregation also suggests potential utility in supporting pancreatic health and managing aspects of metabolic syndrome.

3.CLINICAL EFFICACY OF PRODUCT

Clinical and preclinical studies have demonstrated that Yakuchinone B effectively reduces oxidative damage in neuronal cells, leading to improved cell viability and reduced apoptosis. In models of skin inflammation and carcinogenesis, it has shown efficacy in downregulating pro-inflammatory cytokines and enzymes. Furthermore, its derivatives have exhibited promising results in protecting β-cells from toxicity, indicating its potential in therapeutic strategies for conditions like type 2 diabetes and age-related cognitive decline.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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