Chemicals

α-mangostin CAS NO.6147-11-1

<p>Alpha-Mangostin is a natural xanthone compound primarily extracted from the pericarp of the Garcinia mangostana fruit, renowned for its potent antioxidant and anti-inflammatory properties. This bioactive ingredient is widely utilized in the nutraceutical and pharmaceutical industries due to its ability to support joint health, reduce inflammation, and provide cellular protection against oxidative stress. It is pa…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
α-mangostin
CAS NO.
6147-11-1
Appearance
Fine, light yellow to off-white crystalline powder with minimal odor
Molecular Formula
C24H26O6
Molecular Weight
410.46 g/mol
Purity (RP-HPLC)
≥98%
Solubility

Soluble in DMSO, methanol, ethanol; sparingly soluble in water; insoluble in hexane

Endotoxin≤ 0.1 EU/mg (LAL test), suitable for cell culture and in vivo applications
Biological Activity
Potent antioxidant, anti-inflammatory, and anti-proliferative activity; inhibits NF-κB, COX-2, and VEGF pathways
Storage Conditions
Store in a cool, dry place at 2–8°C; protected from light; avoid moisture and prolonged exposure to air
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Alpha-Mangostin exerts its effects through multiple pathways, including the inhibition of key inflammatory mediators such as COX-2 and the modulation of signaling pathways like Wnt/β-catenin. It functions as a potent antioxidant by scavenging free radicals and reducing reactive oxygen species (ROS) formation, while also demonstrating anti-angiogenic properties by inhibiting VEGF-induced endothelial cell proliferation and migration. Additionally, it induces apoptosis in cancer cells through mitochondrial pathways and modulates immune responses by activating STING (Stimulator of Interferon Genes), thereby enhancing the body's defense mechanisms.

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2.PRODUCT INDICATIONS

This product is indicated for individuals seeking natural support for inflammatory conditions, joint discomfort, and oxidative stress-related issues. It is commonly used in dietary supplements aimed at promoting cardiovascular health, managing metabolic disorders, and supporting immune function. Alpha-Mangostin is also incorporated into cosmeceutical products for its skin-protective benefits, helping to combat signs of aging and improve skin elasticity. Its broad-spectrum activity makes it suitable for formulations targeting anti-aging, weight management, and overall vitality.

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3.CLINICAL EFFICACY OF PRODUCT

Clinical studies have demonstrated that Alpha-Mangostin effectively reduces markers of inflammation and oxidative damage in various models. It has shown promising results in inhibiting the replication of viruses such as Dengue and exhibiting strong antifungal activity against Candida albicans, with low cytotoxicity to human cells. Research also supports its efficacy in suppressing tumor growth and inducing apoptosis in cancer cells, particularly in breast and oral cancers. Furthermore, it has been shown to improve insulin sensitivity and protect against streptozotocin-induced pancreatic damage, highlighting its potential in managing diabetes and metabolic syndromes.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: Alpha-Mangostin, Garcinia Mangostana, Xanthone, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antifungal, Natural Supplement, Bioactive Compound, STING Agonist, Apoptosis Inducer, COX-2 Inhibitor, VEGF Inhibitor, Wnt Signaling, Metabolic Health, Skin Care, Nutraceutical, Pharmaceutical Ingredient, Traditional Medicine

, Supplier, Manufacturer, Bulk order,  Pharmaceutical.


If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553