Pectolinarin CAS NO.28978-02-1
<p>Pectolinarin is a high-purity natural flavonoid glycoside primarily extracted from plants of the <em>Cirsium</em>genus, such as <em>Cirsium japonicum</em>. It is characterized by its potent anti-inflammatory, antioxidant, and neuroprotective properties, making it a valuable compound for research in metabolic disorders, neurodegenerative diseases, and cancer biology. This product is supplied as a fine powder with …
About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Pectolinarin |
| CAS NO. | 28978-02-1 |
| Appearance | Fine off - white to light yellow powder |
| Molecular Formula | C29H34O15 |
| Molecular Weight | 622.57 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in DMSO, methanol, ethanol; partially soluble in water |
| Endotoxin | < 0.001 EU/mg (Tested by limulus amebocyte lysate assay) |
| Biological Activity | Exhibits significant anti - inflammatory, antioxidant, and neuroprotective activities; modulates PI3K/Akt signaling pathway to inhibit cell proliferation and induce apoptosis |
| Storage Conditions | Store at - 20°C in a dry, dark place; avoid repeated freeze - thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Pectolinarin exerts its biological effects primarily by modulating key inflammatory and cell survival pathways. It functions as a potent inhibitor of pro-inflammatory cytokines, effectively reducing the secretion of IL-6 and IL-8, and suppressing the production of inflammatory mediators like PGE2 and NO. Furthermore, it induces apoptosis and inhibits cell proliferation by inactivating the PI3K/Akt signaling pathway, which is crucial for cell growth and survival in various pathological conditions.

2.PRODUCT INDICATIONS
This product is indicated for research applications focused on inflammation, oxidative stress, and cellular apoptosis. It is particularly suitable for studies investigating neurodegenerative disorders, such as Alzheimer's disease, due to its ability to protect against amyloid-beta-induced neurotoxicity. Additionally, it is used in research on metabolic diseases, cancer cell proliferation, and as a model compound for studying the effects of natural flavonoids on immune response and cellular signaling.

3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies have demonstrated that Pectolinarin exhibits significant dose-dependent analgesic and anti-inflammatory activities in animal models. It has been shown to alleviate lipopolysaccharide (LPS)-induced acute liver and kidney injury by regulating metabolic pathways. In cellular models, it enhances cell viability under stress conditions, inhibits ROS generation, and modulates the expression of apoptosis-related proteins, confirming its potential as a therapeutic agent for inflammation-related and degenerative diseases.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Pectolinarin, Anti-inflammatory, Antioxidant, Neuroprotective, PI3K/Akt inhibitor, Flavonoid, Natural Product, Research Chemical, Cytokine Inhibitor, Apoptosis Inducer, Supplier, Manufacturer, Bulk order, Pharmaceutical.
If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553