Pennogenin 3-O-β-chacotrioside CAS NO.55916-52-4
<p>Pennogenin 3-O-β-chacotrioside is a high-purity natural compound extracted from the traditional medicinal plant <em>Paris polyphylla</em>(Chonglou). It is a steroidal saponin known for its potent biological activity, particularly in modulating cellular processes such as autophagy. This product is primarily used as a reference standard in pharmaceutical research and quality control for herbal medicine development,…
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Pennogenin 3-O-β-chacotrioside |
| CAS NO. | 55916-52-4 |
| Appearance | Typically presented as a white to off - white powder (subject to actual batch characteristics) |
| Molecular Formula | C45H72O17 |
| Molecular Weight | 885.04 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in some polar organic solvents (e.g., methanol, DMSO), limited solubility in water (specific solubility may vary depending on experimental conditions) |
| Endotoxin | Low - level endotoxin (if applicable, meet relevant pharmaceutical or research - grade endotoxin limits) |
| Biological Activity | Modulates autophagy pathway, upregulates autophagy - related proteins (e.g., LC3, Beclin - 1), exhibits potential anti - tumor and anti - inflammatory activities by promoting the degradation of damaged cellular components and inhibiting abnormal cell proliferation |
| Storage Conditions | Store at low temperature (e.g., 2 - 8°C) in a dry, dark place, away from direct sunlight and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The compound exerts its effects primarily by modulating the autophagy pathway. It functions by upregulating key autophagy-related proteins, specifically increasing the expression of LC3 and Beclin-1. This action promotes the degradation of damaged cellular components and inhibits abnormal cell proliferation, which is a critical mechanism underlying its observed anti-cancer and anti-inflammatory activities. This makes it a valuable molecule for studying cell death and survival signaling pathways.

2.PRODUCT INDICATIONS
Pennogenin 3-O-β-chacotrioside is indicated for use in scientific research focused on oncology and metabolic disorders. It is particularly relevant for studies investigating colorectal cancer, where it has shown potential to inhibit tumor growth. Additionally, its role in enhancing mitochondrial oxidative capacity suggests applications in research related to lipid metabolism disorders and hypertrophied lipid accumulation, making it a candidate for metabolic disease models.

3.CLINICAL EFFICACY OF PRODUCT
While primarily used in preclinical research, studies have demonstrated that Pennogenin 3-O-β-chacotrioside exhibits significant anti-colorectal cancer activity. It has been shown to induce autophagy in cancer cells, leading to cell death and potentially enhancing the efficacy of chemotherapeutic agents like doxorubicin. Its ability to attenuate hypertrophied lipid accumulation by improving mitochondrial function also points to its potential therapeutic value in managing metabolic syndromes, although clinical validation in humans is still pending.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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