Nortrachelogenin CAS NO.34444-37-6

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

The primary mechanism of action of Nortrachelogenin involves the disruption of cellular membranes and the inhibition of key signaling pathways. In antibacterial applications, it exerts its effect by disorganizing and perturbing the cytoplasmic membrane of bacteria, leading to membrane depolarization and increased permeability, which ultimately results in cell death. In cancer research, it functions by inhibiting the Akt signaling pathway and receptor tyrosine kinases, thereby sensitizing cancer cells to apoptosis-inducing agents like TRAIL.

2.PRODUCT INDICATIONS

Nortrachelogenin is indicated for research use in the study of anti-leukemic and anti-tumor activities, as well as for investigating its effects on the central nervous system. It is particularly relevant for researchers focusing on prostate cancer, leukemia, and antibiotic-resistant bacterial strains. The product is intended for laboratory use by scientists and researchers in pharmacology, biochemistry, and oncology, and is not for human or veterinary therapeutic use.

3.CLINICAL EFFICACY OF PRODUCT

Clinical efficacy data, primarily derived from preclinical studies, demonstrate that Nortrachelogenin is a potent sensitizer of prostate cancer cells to TRAIL-induced apoptosis. It has shown significant efficacy in inhibiting the growth of malignant cells without affecting non-malignant counterparts, highlighting its potential as a therapeutic candidate for cancer treatment. Additionally, its antibacterial properties against pathogens like Escherichia coliO157 further underscore its broad-spectrum biological activity.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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