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Chemicals
Rebaudioside B CAS NO.58543-17-2
<p><strong>Rebaudioside B</strong> (CAS NO. 58543-17-2) is a high-purity, naturally occurring <strong>steviol glycoside</strong> extracted from the leaves of the <em>Stevia rebaudiana</em>Bertoni plant. It is a diterpene glycoside approximately 150-200 times sweeter than sucrose, but with a distinct sweetness profile and lower bitterness compared to other major steviol glycosides like Rebaudioside A. Primarily used …
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Rebaudioside B |
| CAS NO. | 58543-17-2 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C38H60O18 |
| Molecular Weight | 804.87 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Highly soluble in water (≥100 mg/mL at 25°C); soluble in ethanol, methanol; insoluble in non-polar solvents like hexane |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | High-intensity natural sweetener, approximately 300–400 times sweeter than sucrose; non-caloric, suitable for sugar-free and low-calorie food formulations |
| Storage Conditions | Store in a cool, dry place at 2–8°C, sealed tightly to prevent moisture absorption. Avoid exposure to direct light and high temperatures. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
As a Sweetener: Rebaudioside B functions by binding to the sweet taste receptors (T1R2/T1R3) on the human tongue, eliciting a potent sweet sensation without being metabolized for caloric energy, as it passes through the body largely unchanged.
For Potential Therapeutic Effects (based on general steviol glycoside research):
- Anti-diabetic Potential: Studies suggest steviol glycosides may enhance insulin secretion from pancreatic β-cells (insulinotropic effect) and improve insulin sensitivity in peripheral tissues, helping regulate blood glucose levels.
- Anti-hypertensive Potential: They may act as calcium channel blockers in vascular smooth muscle, promoting vasodilation and reducing blood pressure. They also increase sodium excretion and urine output (diuretic and natriuretic effects).
- Anti-inflammatory & Antioxidant Activity: Rebaudioside B may help reduce the production of pro-inflammatory cytokines and act as a free radical scavenger.
2.PRODUCT INDICATIONS
This product is indicated for formulation and research in:
- Food & Beverage Industry: As a bulk natural sweetener in sugar-free, reduced-calorie, and diabetic-friendly products, including soft drinks, dairy, confectionery, and baked goods.
- Nutraceuticals & Dietary Supplements: In formulations aimed at weight management, blood sugar support, and metabolic health.
- Pharmaceutical Research: As a candidate or excipient in studies for developing therapies for diabetes, hypertension, and metabolic syndrome.
- Cosmetic Applications (Emerging): Occasionally used in oral care products (toothpaste, mouthwash) for its sweetening and potential anti-cariogenic properties.
3.CLINICAL EFFICACY OF PRODUCT
While Rebaudioside B itself has fewer dedicated human clinical trials compared to Rebaudioside A, the efficacy of steviol glycosides as a class is well-established:
- Sweetening Efficacy: Recognized as safe (GRAS status in many countries) and effective in providing significant sweetness without calories or glycemic impact, supporting weight management and diabetes care.
- Blood Glucose & Insulin Response: Clinical studies on stevia extracts consistently show no effect on raising blood glucose or insulin levels, making them suitable for diabetics. Some studies indicate a potential to improve postprandial glucose and insulin responses.
- Blood Pressure Modulation: Several human trials on stevioside (a related glycoside) demonstrate a modest but significant reduction in systolic and diastolic blood pressure in hypertensive patients. Similar effects are postulated for Rebaudioside B.
- Safety Profile: Extensive toxicological and clinical data support the safety of high-purity steviol glycosides like Rebaudioside B for
- human consumption.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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