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Chemicals
Tripeptide-3 CAS NO.126828-32-8
<p>Tripeptide-3, commercially known as Syn-AKE, is a synthetic peptide designed to mimic the muscle-relaxing properties of Waglerin-1, a component found in Temple Viper venom. It functions as a reversible antagonist of muscular nicotinic acetylcholine receptors, specifically targeting the neuromuscular junction to inhibit muscle contraction. This mechanism makes it a highly sought-after ingredient in anti-aging and …
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Tripeptide-3 |
| CAS NO. | 126828-32-8 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₅H₂₆N₆O₄ |
| Molecular Weight | 354.41/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Highly soluble in water (≥50 mg/mL), soluble in dilute aqueous buffers; slightly soluble in ethanol |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Promotes fibroblast proliferation and collagen synthesis; enhances skin elasticity, reduces fine lines and wrinkles; supports skin barrier repair and anti-aging effects in cosmetic formulations |
| Storage Conditions | Store at 2°C to 8°C for short-term (≤6 months); long-term at -20°C to -80°C in a dry, dark environment; avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The mechanism of action of Tripeptide-3 involves its selective binding to the muscular nicotinic acetylcholine receptors (mnAChR) at the neuromuscular junction. By competing with acetylcholine for binding at specific sites on the receptor, it prevents the influx of sodium ions that is necessary for muscle depolarization and subsequent contraction. This reversible blockade effectively relaxes the underlying facial muscles, leading to a reduction in the repetitive muscle movements that cause the formation of expression lines and wrinkles on the skin's surface.
2.PRODUCT INDICATIONS
Tripeptide-3 is indicated for use in topical skincare products targeting the reduction of facial wrinkles, particularly those caused by repetitive muscle contractions such as crow's feet, forehead lines, and frown lines. It is also utilized in formulations aimed at improving skin firmness and elasticity by reducing muscle tension. The peptide is suitable for inclusion in serums, creams, and eye patches designed for individuals seeking to diminish the visible signs of aging without the use of injectable neurotoxins.
3.CLINICAL EFFICACY OF PRODUCT
Clinical evaluations of Tripeptide-3 have demonstrated its efficacy in significantly reducing the visibility of wrinkles. Studies involving human volunteers have shown that topical application of formulations containing this peptide can lead to a reduction in wrinkle depth and visibility. For instance, data from manufacturer studies indicate that a 28-day application regimen can result in up to a 52% reduction in wrinkle appearance, validating its role as an effective topical anti-aging agent.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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Global Technology Co., Ltd.
