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Chemicals
Tripeptide-1 CAS NO.72957-37-0
<p><strong>Tripeptide-1</strong> (CAS NO. 72957-37-0) is a synthetic, high-purity tripeptide with the amino acid sequence <strong>Gly-His-Lys (GHK)</strong>. It is the core peptide sequence of the widely acclaimed <strong>GHK-Cu complex</strong> (copper peptide), but without the bound copper ion. In its free form, Tripeptide-1 (GHK) is a potent <strong>signal peptide</strong> that plays a fundamental role in cellula…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Tripeptide-1 |
| CAS NO. | 72957-37-0 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₃H₂₀N₄O₃ |
| Molecular Weight | ~ 280.3 Da |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions. It is recommended to first dissolve in a small volume of sterile water to prepare a 0.1–1.0 mg/mL stock solution. |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Tripeptide‑1 (GHK) is a naturally occurring copper‑binding peptide that promotes collagen synthesis, wound healing, and skin remodeling. It is widely used in cosmetic and dermatological research for its anti‑aging, antioxidant, and tissue‑repair properties. Bioactivity can be validated in cell‑based assays (e.g., collagen production, cell migration). |
| Storage Conditions | Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability. Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Tripeptide-1 functions by chelating copper ions to form a bioactive complex that activates multiple signaling pathways involved in tissue regeneration. This complex stimulates collagen and elastin synthesis by upregulating gene expression in fibroblasts, enhances extracellular matrix deposition, and exhibits antioxidant properties by reducing oxidative stress. Additionally, it modulates inflammatory responses and promotes angiogenesis, collectively contributing to improved skin barrier function and accelerated wound healing.
2.PRODUCT INDICATIONS
This peptide is indicated for research applications in dermatology, cosmetics science, and wound healing studies. It is utilized in in vitro cell culture models to investigate collagen production, fibroblast proliferation, and matrix metalloproteinase regulation. In cosmetic formulation development, Tripeptide-1 serves as an active ingredient for anti-aging skincare products targeting fine lines, wrinkles, and skin elasticity. It is also employed in preclinical wound healing models to evaluate tissue repair efficacy.
3.CLINICAL EFFICACY OF PRODUCT
While Tripeptide-1 has demonstrated promising results in preclinical studies showing enhanced collagen synthesis and improved skin appearance in ex vivo models, it lacks comprehensive clinical trial data for therapeutic use. Topical formulations containing this peptide have shown cosmetic benefits in some consumer studies, but these findings are not equivalent to regulated clinical efficacy. The compound remains primarily a research tool and cosmetic ingredient without FDA approval for medical indications.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:business@huanqiukeji9.com
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