Tetrapeptide-30 CAS NO.1036207-61-0

Tetrapeptide-30 (CAS NO. 1036207-61-0) is a synthetic, high-purity tetrapeptide engineered for advanced cosmetic and dermatological applications. This biomimetic peptide is specifically designed to regulate melanogenesis (skin pigmentation) by inhibiting the activity of the key enzyme tyrosinase. It is a potent skin-brightening and anti-pigmentation agent…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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Peptides

About this product

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Tetrapeptide-30
CAS NO.	1036207-61-0
Appearance	White to off-white lyophilized powder
Molecular Formula	C22H40N6O7
Molecular Weight	500.59 g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water (≥50 mg/mL), soluble in dilute aqueous buffers; slightly soluble in DMSO
Endotoxin	< 1.0 EU/mg
Biological Activity	Inhibits tyrosinase gene expression and melanocyte activation; reduces UVB-induced pro-inflammatory cytokines (IL-6, IL-8, TNF-α) and POMC; lightens hyperpigmentation, evens skin tone, and reduces post-inflammatory pigmentation
Storage Conditions	Store at -20°C to -80°C in a dry, dark, sealed container; avoid repeated freeze-thaw cycles; stable for 24 months under recommended storage.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Tetrapeptide-30 operates through a targeted dual-action mechanism to control pigmentation at the cellular level:

Proteasome Activation & MITF Degradation: It stimulates the activity of the proteasome, the cellular machinery responsible for degrading proteins. This action specifically accelerates the breakdown of MITF (Microphthalmia-associated Transcription Factor), a master regulator that controls the expression of multiple enzymes involved in melanin synthesis, including tyrosinase.
Downregulation of Melanogenic Enzymes: By reducing MITF levels, Tetrapeptide-30 leads to a decrease in the production of tyrosinase and other key pigmentation enzymes (TYRP1, TYRP2). This results in a reduction of melanin synthesis within melanocytes.
Selective Action: It specifically targets hyperactive melanocytes without affecting normal melanin production, making it a focused solution for treating hyperpigmentation.

2.PRODUCT INDICATIONS

This product is indicated for cosmetic science and the development of high-performance skin-brightening and pigmentation-correcting products. Key applications include:

As a primary active in skin-brightening serums, creams, and spot treatments designed to fade dark spots, melasma, and post-inflammatory hyperpigmentation (PIH).
In formulations aimed at evening overall skin tone and reducing sun-induced or age-related pigmentation.
For professional and clinical-grade products targeting stubborn hyperpigmentation.
As part of comprehensive anti-aging regimens to address photoaging concerns like sun spots and uneven texture.
In products for preventative skincare to inhibit the formation of new dark spots.

3.CLINICAL EFFICACY OF PRODUCT

Tetrapeptide-30 is supported by robust in vitro data and clinical studies on cosmetic formulations. Evidence demonstrates its efficacy as a potent and well-tolerated brightening agent:

Significant Reduction in Pigmentation: Clinical studies show a visible lightening of dark spots and hyperpigmented areas, with improvements in overall skin tone evenness.
High Efficacy Profile: It is recognized for its strong inhibitory effect on melanin production, comparable to or exceeding that of some traditional brightening agents, but with a favorable safety profile.
Suitable for Sensitive Skin: Its targeted mechanism often allows for effective brightening with lower irritation potential compared to ingredients like hydroquinone or high-concentration acids.
Improvement in Skin Radiance: Regular use leads to a brighter, more luminous complexion.
4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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