Chemicals

Palmitoyl Tetrapeptide-3 CAS NO.221227-05-0

<p><strong>Palmitoyl Tetrapeptide-3</strong> (also known as <strong>Rigin™</strong> or <strong>Pal-GQPR</strong>) is a synthetic, lipidated peptide widely used in the cosmetic industry as a <strong>dermo-restructuring and anti-wrinkle active ingredient</strong>. It is a modified version of a natural peptide sequence found in the immunoglobulin G (IgG) molecule. The addition of a palmitoyl fatty acid chain (palmitoyl…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
Source categories

About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Palmitoyl Tetrapeptide-3
CAS NO.
221227-05-0
Appearance
White to off-white lyophilized powder
Molecular Formula
C₃₉H₇₂N₁₂O₈
Molecular Weight
885.06g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions.

Endotoxin< 1.0 EU/mg
Biological Activity
Palmitoyl Tetrapeptide‑3 (also known as Palmitoyl‑GHK) is a lipopeptide used in cosmetics for its reported skin‑repairing, collagen‑stimulating, and anti‑inflammatory properties. It is designed to enhance skin elasticity, hydration, and barrier function.
Storage Conditions
Lyophilized powder: Store at –20 °C or below, desiccated, protected from light.
Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Palmitoyl Tetrapeptide-3 penetrates the epidermis and acts on dermal fibroblasts to stimulate the production of collagen types I and III, as well as elastin and glycosaminoglycans, thereby improving skin firmness and elasticity. It also modulates inflammatory pathways and supports extracellular matrix remodeling, enhancing skin barrier integrity and reducing the appearance of fine lines and wrinkles through structural reinforcement of the dermal layer.

upload/attachment/image/202603/25/1774422131784312817f51275e5daf63ebc5d1953b_local.pngupload/attachment/image/202603/25/1774422161335edea7c35ac101b716e5fcae5735cb_local.png

2.PRODUCT INDICATIONS

This lipopeptide is indicated for research and development of topical cosmetic formulations targeting anti-aging, skin repair, and barrier enhancement, including products for facial serums, eye creams, and neck treatments. It is used in in vitro and ex vivo models to evaluate collagen synthesis, skin elasticity, and wound healing properties, with applications in formulations addressing photoaging, loss of firmness, and compromised skin barrier due to aging and environmental stressors.

upload/attachment/image/202603/25/17744221942609ddea58fdea5bfe40cee275ee15b1_local.png

3.CLINICAL EFFICACY OF PRODUCT

Clinical studies on formulations containing Palmitoyl Tetrapeptide-3 demonstrate improvements in skin elasticity, firmness, and reduction in the appearance of fine lines and wrinkles after 4 to 12 weeks of topical application, with enhanced skin hydration and barrier function observed in subjects with aging and photoaged skin. While these results are supportive, data are primarily from manufacturer-sponsored trials and small-scale studies, and the ingredient is often used in combination with other anti-aging actives, positioning it as a cosmetic ingredient with evidence for skin-repairing and firming benefits.

upload/attachment/image/202603/25/17744222181b3b5af2c99c1dfa65c58b4ead7186d9_local.png

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

upload/attachment/image/202601/20/1768872924be74a0641f7ddbf20e541c97f2066c5c_local.jpg


Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: PalmitoylTetrapeptide3, #AntiAging, #CollagenBooster, #SkinFirming, #Peptide, #WrinkleReduction, #SkincareScience, #Rejuvenation, #Lipopeptide, #Dermacosmetics


If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85244219157