Chemicals

Urocortin III, human CAS NO.357952-09-1

<p>Urocortin III, human (CAS NO. 357952-09-1) is a high‑purity synthetic peptide designed for neuroscience, endocrinology, and metabolic research.It serves as a selective ligand for corticotropin‑releasing factor receptors, enabling precise investigation of stress, metabolism, and related physiological pathways.</p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Urocortin III, human
CAS NO.
357952-09-1
Appearance
White to off-white lyophilized powder
Molecular Formula
C185H307N53O50S2
Molecular Weight
 4137.96g/mol 
Purity (RP-HPLC)
≥95.0% (can be customized to ≥98.0%)
Solubility

Soluble in water, 0.1 M acetic acid, or PBS (pH 7.0‑7.4)

Endotoxin< 1.0 EU/mg
Biological Activity
Selective CRF₂ receptor agonist; involved in stress response, anxiety, and energy balance regulation.
Storage Conditions
Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C.
Stock Location
Stock in USA
MOQ
1mg


1.MECHANISM OF ACTION

Urocortin III, human functions by selectively binding to corticotropin‑releasing factor type 2 (CRF₂) receptors, activating intracellular signaling cascades that modulate stress responses, energy balance, and cardiovascular function. This receptor‑specific interaction helps regulate neuroendocrine and autonomic pathways involved in adaptation to physiological challenges.


2.PRODUCT INDICATIONS

This peptide is used in preclinical studies of stress‑related disorders, anxiety, metabolic syndrome, and cardiovascular diseases. It is also applied in drug‑discovery assays targeting CRF₂ receptors and in research exploring the interplay between stress, inflammation, and metabolic homeostasis.


3.CLINICAL EFFICACY OF PRODUCT

Preclinical data demonstrate that Urocortin III, human can attenuate stress‑induced behavioral and physiological changes, improve metabolic parameters, and reduce inflammatory markers in experimental models. These findings support its potential as a lead compound for developing novel therapeutics aimed at stress‑related and metabolic conditions.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.