[Ile8]-Oxytocin

<p>[Ile⁸]-Oxytocin is a synthetic analog of oxytocin where the leucine residue at position 8 is replaced with isoleucine. This modification alters its interaction with oxytocin receptors, making it a valuable research tool for studying receptor pharmacology, structure-activity relationships, and the differential signaling of oxytocin-like peptides in neuroendocrine and reproductive systems.</p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Ile8]-Oxytocin
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C43H66N12O12S2
Molecular Weight	1007.2 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, dilute acetic acid (0.1% v/v), or phosphate‑buffered saline (PBS). Recommend dissolving in 0.1% acetic acid to prepare a 0.1–1.0 mg/mL stock solution.
Endotoxin	< 1.0 EU/mg
Biological Activity	[Ile⁸]‑Oxytocin is an analog of oxytocin with altered receptor‑binding and functional properties. It exhibits partial agonist/antagonist activity at the oxytocin receptor and is used in studies of oxytocin receptor pharmacology, uterine contraction, and social behavior. Bioactivity should be validated in receptor‑binding or functional assays (e.g., calcium mobilization, uterine‑strip contraction).
Storage Conditions	Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability. Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The peptide acts primarily as a partial agonist or antagonist at the oxytocin receptor, binding with altered affinity compared to native oxytocin. This interaction modulates G protein-coupled signaling pathways, particularly those involving phospholipase C and intracellular calcium mobilization, leading to modified effects on uterine contraction, social bonding, and stress responses, thereby enabling the dissection of specific receptor-ligand interactions.

2.PRODUCT INDICATIONS

[Ile⁸]-Oxytocin is indicated for research applications in neuroendocrinology and pharmacology, including studies of oxytocin receptor signaling, the development of oxytocin-based therapeutics, and investigations into social behavior, parturition, and lactation mechanisms. It serves as a critical tool for in vitro and in vivo models aiming to understand the nuanced roles of oxytocin and its analogs.

3.CLINICAL EFFICACY OF PRODUCT

As a research-grade analog, [Ile⁸]-Oxytocin has no established clinical efficacy and is not approved for therapeutic use. Its value lies in preclinical research, where it helps identify and characterize oxytocin receptor modulators that may inform the development of future clinical candidates for conditions such as autism, anxiety, and obstetric complications, though it is not a treatment itself.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Shipping Methods
Main Method: International Air Freight

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