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Chemicals
Palmitoyl Isoleucine CAS NO. 54617-29-7
<p>Palmitoyl Isoleucine is a lipo-amino acid cosmetic ingredient designed to enhance skin volume and firmness by targeting adipocytes and dermal fibroblasts. Supplied as a stable, white to off-white powder for topical formulations, it functions as a multifunctional active in anti-aging and body-contouring products, improving skin elasticity and reducing the appearance of sagging through structural support at the der…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Palmitoyl Isoleucine |
| CAS NO. | 54617-29-7 |
| Appearance | Fine, white to off - white powder. |
| Molecular Formula | C₂₂H₄₃NO₄ |
| Molecular Weight | 353.58 g/mol |
| Amino Acid Sequence | The product is palmitoylated isoleucine, where a palmitoyl group (C16H31CO−) is attached to the isoleucine amino acid. |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in organic solvents such as dimethyl sulfoxide (DMSO), methanol, and chloroform. It has limited solubility in water. |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Palmitoyl Isoleucine has been shown to play a role in skin health. It can help in the formation of lipid lamellae in the stratum corneum, which is crucial for maintaining skin barrier function. |
| Storage Conditions | Store at - 20°C in a dry, well - ventilated place, away from light and moisture. Protect from strong oxidizing agents. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Palmitoyl Isoleucine penetrates the skin and modulates fibroblast contractility and extracellular matrix (ECM) organization, increasing collagen-I gene expression and upregulating serpin-1H while inhibiting MMP-2 and boosting TIMP-2 to protect ECM from degradation. It also activates proteasome-mediated detoxification and scavenges hydroxyl radicals, supporting adipocyte function and reducing the formation of non-functional "MAD" adipocytes to maintain tissue volume and resilience.
2.PRODUCT INDICATIONS
This ingredient is indicated for research and development of topical cosmetic formulations targeting facial and body skin firming, volume restoration, and anti-aging effects, including eye creams, facial serums, and bust/body contouring products. It is used in in vitro and ex vivo models to evaluate adipocyte health, fibroblast contractility, and ECM remodeling, with applications in products addressing wrinkles, loss of elasticity, and sagging skin associated with aging and photoaging.
3.CLINICAL EFFICACY OF PRODUCT
Clinical data for Palmitoyl Isoleucine are limited to manufacturer-sponsored studies and formulations combining it with other palmitoyl peptides and antioxidants, which report improvements in skin elasticity, dermal density, and wrinkle reduction after 4 weeks of topical use. However, no large, independent, peer-reviewed trials confirm its standalone efficacy; it remains a cosmetic ingredient with supportive but preliminary evidence for aesthetic benefits, lacking regulatory approval for therapeutic claims.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: PalmitoylIsoleucine, #SensitiveSkin, #BarrierRepair, #SkinSoothing, #Biomimetic, #AntiRedness, #LipoaminoAcid, #SkinCareScience, #Hydration, #Dermocosmetics
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85296236544
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Global Technology Co., Ltd.
