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Chemicals
Urotensin II (Frog)
<p>Urotensin II (Frog) is a premium frog-specific neuropeptide with a defined molecular formula (C₆₉H₉₆N₁₆O₁₉S₂) and molecular weight (1517.76 g/mol). As a professional Urotensin II supplier, we deliver this product with ≥98% purity (RP-HPLC), low endotoxin levels, and intact disulfide bonds, ensuring potent UT receptor agonist activity. Tailored for amphibian physiology, cardiovascular, and comparative biology rese…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Urotensin II (Frog) |
| CAS NO. | \ |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₆₉H₉₆N₁₆O₁₉S₂ |
| Molecular Weight | g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in distilled water (≥ 1 mg/mL), PBS buffer (pH 7.2–7.4, ≥ 1.5 mg/mL), and DMSO (≥ 2 mg/mL) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Potent agonist of urotensin II receptor (UT); regulates vascular tone, cardiovascular function, and osmotic balance in frog models; modulates neuronal excitability and inflammatory responses; exhibits species-specific activity with high affinity for frog UT receptors |
| Storage Conditions | Store at -20°C or below, desiccated in an airtight, light-protected container |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Urotensin II (Frog) exerts its biological effects through high-affinity binding to the urotensin II receptor (UT)—a G-protein-coupled receptor (GPCR) widely expressed in frog vascular tissues, cardiovascular organs, and the central nervous system. The peptide’s frog-specific sequence and dual disulfide bonds optimize conformational stability, ensuring high selectivity and affinity for frog UT receptors, with minimal cross-reactivity to UT receptors of other species.
2.PRODUCT INDICATIONS
UT receptor research: Investigation of UT receptor structure-function relationships in frog models, serving as a standard ligand for receptor activation assays, agonist/antagonist screening, and binding affinity analysis.
Amphibian physiology research: Study of vascular tone regulation, cardiovascular function, and osmotic balance in frogs, supporting exploration of amphibian-specific physiological mechanisms.
Cardiovascular research: Evaluation of the peptide’s role in modulating frog vascular smooth muscle activity, aiding studies on comparative cardiovascular physiology and pathology.
3.CLINICAL EFFICACY OF PRODUCT
Urotensin II (Frog) is widely utilized in amphibian-focused preclinical research, with proven efficacy in both in vitro and in vivo frog models. In frog vascular smooth muscle cell assays, it exhibits potent UT receptor activation, effectively modulating contraction/relaxation responses with sustained activity due to its intact disulfide bonds—ensuring reliable and reproducible experimental results.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
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Global Technology Co., Ltd.
