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Chemicals
Neurotensin (Frog)
<p><br/></p><div class="ybc-p">Neurotensin (Frog) is a synthetic peptide representing the amphibian (frog) isoform of the neurotensin (NT) neuropeptide family. This research-grade peptide exhibits structural similarity to mammalian neurotensin but with specific amino acid sequence variations. It serves as a valuable tool for comparative neuroendocrinology studies, allowing researchers to investigate the evolution, r…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Neurotensin (Frog) |
| CAS NO. | / |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C70H115N23O17 |
| Molecular Weight | 1550.84/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Soluble in water (up to 5 mg/mL), dilute acetic acid, or DMSO |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Potent agonist of neurotensin receptors (NTS1 and NTS2). Modulates central nervous system function, pain perception, and dopamine signaling |
| Storage Conditions | Store desiccated at -20°C to -80°C; avoid repeated freeze-thaw cycles. Stable for 2–3 years under proper storage. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Similar to its mammalian counterpart, Frog Neurotensin is believed to exert its biological effects by activating neurotensin receptors (primarily NTS1 and NTS2), which are G protein-coupled receptors. Upon binding, it likely initiates signaling cascades involving phospholipase C (PLC) activation, leading to the production of inositol trisphosphate (IP3) and diacylglycerol (DAG), resulting in intracellular calcium mobilization and protein kinase C (PKC) activation.
2.PRODUCT INDICATIONS
This product is indicated for specialized research in evolutionary biology, comparative physiology, and receptor pharmacology. Key applications include: studying the phylogenetic conservation and divergence of the neurotensin system across vertebrates, investigating the receptor binding affinity and functional selectivity of non-mammalian NT peptides on mammalian or amphibian receptors, exploring its physiological roles in amphibian models (e.g., smooth muscle contraction, metabolism), and as a unique ligand in structure-activity relationship (SAR) studies to map critical residues for receptor interaction.
3.CLINICAL EFFICACY OF PRODUCT
Neurotensin (Frog) is not a clinical therapeutic but a research probe for basic science. Its "efficacy" lies in its utility for understanding fundamental biological principles. Research using this peptide provides insights into the evolutionary pressures that shape neuropeptide-receptor systems. By comparing frog and mammalian neurotensin, scientists can identify conserved functional domains critical for receptor activation.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Shipping Methods
Main Method: International Air Freight
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Global Technology Co., Ltd.
