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Chemicals
Activity-Dependent Neurotrophic Factor-14 CAS NO.177159-38-5
<p>Activity-Dependent Neurotrophic Factor-14 (ADNF-14) (CAS NO. 177159-38-5) is a synthetic 14-amino acid peptide derived from the activity-dependent neurotrophic factor (ADNF) protein. This research-grade peptide is a potent, active neuroprotective fragment. It is designed to mimic the protective effects of the parent protein and serves as a crucial tool for studying neuronal survival, synaptic plasticity, and mech…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Activity-Dependent Neurotrophic Factor-14 (ADNF-14) |
| CAS NO. | 177159-38-5 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C58H103N17O17 |
| Molecular Weight | 1310.57/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Highly soluble in deionized water and phosphate-buffered saline |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Potent neurotrophic and neuroprotective peptide. |
| Storage Conditions | Lyophilized powder: Long-term storage at -20°C to -80°C. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
ADNF-14 exerts its neuroprotective effects through a receptor-mediated mechanism, though its specific high-affinity receptor is still under characterization. It is known to interact with cell surface binding sites, triggering intracellular signaling cascades that promote neuronal survival. Its action is highly dependent on neuronal activity ("activity-dependent").
2.PRODUCT INDICATIONS
This product is indicated for in vitro and in vivo research in neuroscience, neuropharmacology, and neurotoxicology. Key applications include: studying mechanisms of neuroprotection against excitotoxicity, oxidative stress, and β-amyloid toxicity; investigating synaptic plasticity, learning, and memory processes; exploring potential therapeutic strategies for neurodegenerative diseases such as Alzheimer's disease; and as a positive control in assays for neuronal survival and viability.
3.CLINICAL EFFICACY OF PRODUCT
ADNF-14 is a preclinical research peptide and not an approved drug. Its "efficacy" is demonstrated in experimental models of neurodegeneration and injury. Studies have shown that ADNF-14 can protect neurons from death induced by various toxins and pathological conditions in cell culture and animal models.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Main Method: International Air Freight
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Global Technology Co., Ltd.
