Chemicals

Prepro-Neuromedin U (104-136) (human)

<p>Prepro-Neuromedin U (104-136) (human) is a high-purity, research-grade synthetic peptide derived from the human neuromedin U precursor.This peptide is designed for studies in neuroendocrinology, metabolism, and gastrointestinal physiology.</p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Prepro‑Neuromedin U (104‑136) (human)
CAS NO.

Appearance
White to off-white lyophilized powder
Molecular Formula
C177H277N47O45
Amino Acid Sequence
H‑Gln‑Tyr‑Phe‑Leu‑Arg‑Pro‑Arg‑Asn‑Ser‑Ala‑Gly‑Tyr‑Leu‑Leu‑Arg‑Glu‑Phe‑Leu‑Gln‑Arg‑Phe‑NH₂ (human NMU prepro‑region residues 104‑136; C‑terminal amidation common)
Molecular Weight
3783.47g/mol 
Purity (RP-HPLC)
≥95.0% (can be customized to ≥98.0%)
Solubility

Soluble in water, dilute acetic acid, or PBS (pH 7.0‑7.4)

Endotoxin< 1.0 EU/mg
Biological Activity
Precursor‑derived fragment of neuromedin U; activates NMU receptors (NMUR1/NMUR2) and regulates smooth muscle contraction, appetite, stress response, and energy homeostasis.
Storage Conditions
Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C.
Stock Location
Stock in USA
MOQ
1mg


1.MECHANISM OF ACTION

Prepro-Neuromedin U (104-136) (human) binds to and activates neuromedin U receptors (NMUR1 and NMUR2), initiating G-protein-coupled signaling pathways that regulate smooth muscle contraction, appetite suppression, and energy homeostasis.


2.PRODUCT INDICATIONS

This peptide is used in preclinical research focused on obesity, metabolic syndrome, gastrointestinal motility disorders, and stress-related physiological responses. It also serves as a tool for investigating neuromedin U signaling in neuroendocrine and cardiovascular systems.


3.CLINICAL EFFICACY OF PRODUCT

In experimental models, Prepro-Neuromedin U (104-136) has demonstrated potent anorexigenic effects and the ability to modulate gastrointestinal smooth muscle activity. These findings support its relevance as a research compound for developing potential therapeutics targeting appetite control and metabolic dysregulation.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.