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Chemicals
Octaneuropeptide
<p>Octaneuropeptide (OP), also known as the Octadecaneuropeptide, is a synthetic neuropeptide derived from the processing of the larger precursor protein, diazepam-binding inhibitor (DBI). This endogenous 18-amino acid peptide (QATVGDVNTDRPGLLDLK) is a high-purity research tool, recognized for its central role in modulating anxiety, stress responses, and neuroendocrine functions, particularly within the GABAergic sy…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Octaneuropeptide |
| CAS NO. | / |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C41H74N12O11 |
| Molecular Weight | 911.1/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in water (≥1 mg/mL), 0.1% TFA aqueous solution, dilute acetic acid and DMSO |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Potent regulator of astroglial calcium signaling (PLC-dependent Ca²⁺ mobilization, EC₅₀ ≈ 0.5–3.0 nM) |
| Storage Conditions | Store at ≤ -20°C in a dry, dark, sealed container. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Octaneuropeptide exerts its effects primarily through interactions with the central-type benzodiazepine receptors (CBR), which are located on the mitochondrial membrane and are part of the mitochondrial permeability transition pore (MPTP). By binding to these receptors, OP antagonizes the action of endozepines, modulates mitochondrial function, and influences GABA_A receptor activity indirectly.
2.PRODUCT INDICATIONS
This product is indicated for advanced neurobiological and pharmacological research. Key applications include: studying the molecular mechanisms of anxiety, stress, and neuroendocrine regulation, investigating the role of the endozepine/OP system in brain disorders, evaluating its effects on food intake and metabolism in rodent models, and serving as a reference peptide in receptor binding studies to characterize CBR-mediated signaling pathways.
3.CLINICAL EFFICACY OF PRODUCT
Octaneuropeptide is a research-grade neuropeptide and not a direct clinical therapeutic. Its "efficacy" lies in its critical role as an endogenous modulator of brain function, providing a valuable model for understanding anxiety and stress disorders at the molecular level.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
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Global Technology Co., Ltd.
