[Nle10]-Neurokinin A (4-10)

<p>[Nle¹⁰]-Neurokinin A (4-10) (CAS NO. 124929-64-0) is a high‑purity, modified tachykinin peptide designed for pharmacological and biochemical research.This selective peptide agonist is optimized for stability and bioactivity in neurokinin receptor studies.<br/></p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Nle¹⁰]-Neurokinin A (4‑10)
CAS NO.
Appearance	White to off-white lyophilized powder
Molecular Formula	C35H56N8O10
Amino Acid Sequence	H‑His‑Lys‑Thr‑Asp‑Ser‑Phe‑Nle‑NH₂ (Neurokinin A residues 4‑10 with norleucine at position 10)
Molecular Weight	748.88g/mol
Purity (RP-HPLC)	≥97.0% (typical for research peptides)
Solubility	Soluble in water, 0.1 M acetic acid, or phosphate‑buffered saline (PBS)
Endotoxin	< 1.0 EU/mg
Biological Activity	Modified tachykinin peptide; selective agonist for the NK₂ receptor, used in studies of smooth muscle contraction, airway reactivity, and neurokinin receptor signaling.
Storage Conditions	Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C.
Stock Location	Stock in USA
MOQ	1mg

1.MECHANISM OF ACTION

[Nle¹⁰]-Neurokinin A (4-10) acts as a selective agonist for the neurokinin‑2 (NK₂) receptor. By binding to NK₂ receptors, it initiates intracellular signaling cascades, such as phospholipase C activation and calcium mobilization, leading to physiological responses including smooth muscle contraction and neuronal excitation.

2.PRODUCT INDICATIONS

This peptide is used in research on smooth muscle physiology, airway reactivity, gastrointestinal motility, and pain signaling. It is also applied in drug‑discovery assays for NK₂ receptor‑targeting compounds and in studies of inflammatory and respiratory disorders.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that [Nle¹⁰]-Neurokinin A (4-10) effectively induces smooth muscle contraction and modulates airway responsiveness in experimental models. While not a therapeutic itself, it provides a valuable tool for validating NK₂ receptor pathways and supporting the development of novel therapeutics for conditions like asthma, irritable bowel syndrome, and chronic pain.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

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