[Des-Gly77,His78] Myelin Basic Protein (68-84), bovine CAS NO.98474-59-0

<p>[Des-Gly77,His78] Myelin Basic Protein (68-84), bovine (CAS NO. 98474-59-0) is a high-purity synthetic peptide derived from bovine myelin basic protein (MBP). This modified peptide, with specific amino acid deletions (Gly77 and His78), is designed for research in neuroimmunology and autoimmune disease studies.</p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

View on supplier website More from this supplier

Source categories

Peptides

About this product

Product information from the supplier.

TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Des-Gly77,His78] Myelin Basic Protein (68-84), bovine
CAS NO.	98474-59-0
Appearance	White to off-white lyophilized powder
Molecular Formula	C73H115N23O26
Amino Acid Sequence	H-Gly-Ser-Leu-Pro-Gln-Lys-Ser-His-Tyr-Gly-Ser-Leu-Pro-Gln-Lys-OH (corresponding to bovine MBP residues 68-84, with deletion of Gly77 and His78)
Molecular Weight	1730.87g/mol
Purity (RP-HPLC)	≥95.0% (typical for custom research peptides)
Solubility	Soluble in water, PBS, or dilute acetic acid solution (0.1-1% acetic acid recommended)
Endotoxin	< 1.0 EU/mg
Biological Activity	Modified MBP epitope; used in autoimmune research (e.g., experimental autoimmune encephalomyelitis/EAE models), T-cell epitope mapping, and multiple sclerosis studies.
Storage Conditions	Store at –20°C (lyophilized) or –80°C (solution). Protect from light and repeated freeze‑thaw cycles.
Stock Location	Stock in USA
MOQ	1mg

1.MECHANISM OF ACTION

This peptide acts as a specific antigenic epitope that can be presented by major histocompatibility complex (MHC) molecules to activate autoreactive T-cells. In experimental models, it helps simulate the immune-mediated attack on myelin sheaths, providing a tool to study the pathogenesis of demyelinating diseases such as multiple sclerosis.

2.PRODUCT INDICATIONS

[Des-Gly77,His78] Myelin Basic Protein (68-84), bovine is primarily used in preclinical research to model autoimmune encephalomyelitis (EAE), investigate T-cell responses, and evaluate potential therapies for multiple sclerosis and other myelin-related disorders. It is also applied in epitope mapping and immunological assay development.

3.CLINICAL EFFICACY OF PRODUCT

As a research tool, this peptide is not intended for direct clinical use. However, it has proven effective in inducing EAE in animal models, enabling the study of disease mechanisms and the screening of immunomodulatory or neuroprotective compounds, thereby supporting translational research aimed at developing new treatments for autoimmune demyelinating conditions.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.