[Tyr9]- β-MSH (porcine); (Tyr49)-β-Lipotropin (41-58) (porcine) CAS NO.198281-81-1

<p>[Tyr⁹]-β-MSH (porcine); (Tyr⁴⁹)-β-Lipotropin (41-58) (porcine) is a high-purity synthetic peptide representing two distinct but related porcine-derived sequences: the Tyr⁹-modified form of β-melanocyte-stimulating hormone (β-MSH) and the Tyr⁴⁹-modified fragment of β-lipotropin (41-58). Both sequences are derived from the same precursor protein and share melanocortin receptor binding properties. Manufactured under…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Tyr9]- β-MSH (porcine); (Tyr49)-β-Lipotropin (41-58) (porcine)
CAS NO.	198281-81-1
Appearance	White to off-white lyophilized powder
Molecular Formula	C101H140N24O30S
Molecular Weight	2202.43 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, dilute acetic acid, DMSO
Endotoxin	< 1.0 EU/mg
Biological Activity	Tyr⁹ modified form of porcine β-melanocyte stimulating hormone; it regulates pigment synthesis, energy balance, and inflammatory response by binding to melanocortin receptors (such as MC1R and MC4R).
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This product contains two bioactive peptide sequences that primarily function through activation of melanocortin receptors (MC1R, MC3R, MC4R, MC5R). Upon receptor binding, these peptides activate G-protein coupled signaling pathways, leading to increased intracellular cAMP levels through adenylate cyclase activation. The downstream effects include regulation of melanogenesis (pigment production), energy homeostasis, appetite regulation, anti-inflammatory responses, and neuroendocrine functions. The Tyr⁹ modification in β-MSH and Tyr⁴⁹ modification in β-lipotropin fragment may influence receptor binding affinity, metabolic stability, or signaling potency compared to native sequences, making this product valuable for structure-activity relationship studies and receptor pharmacology research.

2.PRODUCT INDICATIONS

Melanocortin Receptor Research: Investigation of MC receptor binding, activation, and signaling mechanisms

Comparative Endocrinology: Study of melanocortin system function across species using porcine-specific sequences

Structure-Activity Relationship: Analysis of Tyr modifications on receptor affinity and biological activity

Pigmentation Research: Study of melanogenesis regulation and pigment cell biology

Metabolic Regulation: Investigation of energy balance, appetite control, and metabolic disorders

Anti-inflammatory Research: Exploration of melanocortin-mediated anti-inflammatory pathways

3.CLINICAL EFFICACY OF PRODUCT

High Purity: ≥95% by RP-HPLC with mass spectrometry confirmation of both modified sequences

Sequence Authenticity: Verified Tyr⁹-β-MSH and Tyr⁴⁹-β-lipotropin (41-58) porcine sequences

Biological Activity: Validated in melanocortin receptor binding and functional assays

Species Specificity: Confirmed porcine origin for comparative and species-specific studies

Research Reproducibility: Consistent performance in receptor binding and signaling assays

Low Endotoxin:<1.0 eu="">

Quality Documentation: Certificate of Analysis provided with purity, mass spec, and analytical data

Technical Support: Access to application guidance for melanocortin system research

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.