Chemicals

HCV-1 e2 Protein (554 – 569)

<p><div class="ybc-p">HCV-1 e2 Protein (554-569) is a high-purity synthetic peptide corresponding to a critical functional domain of the Hepatitis C Virus type 1 envelope glycoprotein e2. This 16-amino acid peptide represents a key region involved in viral entry, host cell receptor interaction, and immune recognition. With ≥95% purity verified by RP-HPLC and comprehensive analytical documentation, it provides resear…

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About this product

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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
HCV-1 e2 Protein (554 - 569)
CAS NO.
/
Appearance
White to off-white lyophilized powder
Molecular Formula
C74H111N19O21S3
Molecular Weight
 1699g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in DMSO, PBS (pH 7-8), or an aqueous solution containing a small amount of organic solvent.

Endotoxin< 1.0 EU/mg
Biological Activity
Functional fragments of HCV envelope glycoprotein e2; involved in viral attachment, membrane fusion, and neutralizing antibody recognition, used in HCV entry mechanisms, vaccine design, and neutralizing antibody research.
Storage Conditions
Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

HCV-1 e2 Protein (554-569) functions as a crucial domain within the HCV envelope glycoprotein e2, mediating initial viral attachment and entry into hepatocytes. This peptide region contains specific motifs that interact with host cell surface receptors, including CD81 and other entry factors, facilitating viral docking and membrane fusion. The sequence may also be involved in immune evasion by shielding critical neutralizing epitopes or modulating antibody recognition. In research settings, this peptide competitively inhibits viral entry, blocks receptor binding, and serves as an antigen for characterizing neutralizing antibodies, enabling detailed study of HCV-1 entry mechanisms and host-pathogen interactions.


2.PRODUCT INDICATIONS

Viral Entry Research: Investigation of HCV-1 attachment, receptor binding, and fusion mechanisms
Vaccine Development: Design and evaluation of e2-targeted vaccines and immunogens
Neutralizing Antibody Studies: Characterization of antibody responses and epitope mapping
Therapeutic Discovery: Screening for entry inhibitors and antiviral compounds
Diagnostic Development: Design of serological assays for HCV-1 detection and typing
Structural Virology: Analysis of e2 protein structure-function relationships


3.CLINICAL EFFICACY OF PRODUCT

Biological Relevance: Maintains key functional properties for entry and immunogenicity studies
Sequence Accuracy: Verified 16-amino acid sequence specific to HCV-1 e2 (554-569)
Research Reproducibility: Consistent performance in binding, neutralization, and immunization assays
Low Endotoxin:<1.0 eu="">
Quality Documentation: Certificate of Analysis provided with purity, mass spec, and functional data
Technical Support: Access to application guidance for HCV virology and immunology research


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.