GPC3 (144 – 152)

<p>GPC3 (144-152) is a high-purity synthetic peptide developed for cancer immunotherapy research, specifically targeting hepatocellular carcinoma (HCC). The product specifications, including CAS number, molecular formula, molecular weight, and other key details, are available upon request. This HLA-restricted peptide antigen is designed to stimulate targeted immune responses against GPC3-expressing tumors.</p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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Peptides

About this product

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	GPC3 (144‑152)
CAS NO.
Appearance	White to off-white lyophilized powder
Molecular Formula	C52H69N9O15
Molecular Weight	1060.18g/mol
Amino Acid Sequence	FVGEFFTDV (human GPC3 residues 144‑152, HLA‑A*24:02‑restricted epitope)
Purity (RP-HPLC)	≥95.0%
Solubility	Soluble in DMSO, PBS, or sterile water (may require brief sonication)
Endotoxin	≤1.0 EU/mg
Biological Activity	HLA‑A*24:02‑restricted tumor‑associated antigen peptide; used in hepatocellular carcinoma (HCC) immunotherapy research, T‑cell activation studies, and cancer vaccine development.
Storage Conditions	Store at –20°C, protected from light and moisture. For long-term storage, recommend –80°C.
Stock Location	Stock in USA
MOQ	10mg

1.MECHANISM OF ACTION

GPC3 (144-152) acts as a tumor-associated antigen presented by HLA-A*24:02 molecules on antigen-presenting cells. This presentation activates cytotoxic T lymphocytes (CTLs), which then recognize and eliminate GPC3-positive cancer cells, initiating a specific anti-tumor immune response.

2.PRODUCT INDICATIONS

This peptide is used in the research and development of immunotherapies for hepatocellular carcinoma, including peptide-based vaccines and adoptive T-cell therapies. It is also applied in immunological assays, T-cell activation studies, and preclinical evaluation of combination treatment strategies for GPC3-expressing cancers.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies and early-phase clinical trials indicate that GPC3-targeting peptides can induce antigen-specific T-cell responses and contribute to tumor control in HCC models. Its potential in enhancing immune-mediated tumor regression supports ongoing research into GPC3-directed immunotherapeutic approaches.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.