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Chemicals
gp100 (619-627)
<p>Introducing <strong>gp100 (619–627)</strong>, a premium synthetic peptide engineered for cutting-edge oncology and immunotherapy research. With a precise molecular formula of <strong>C₄₉H₈₂N₁₄O₁₄S</strong> and a molecular weight of <strong>1123.35</strong>, this high-purity antigenic sequence (619–627) targets melanoma cells via MHC class I pathways, enabling robust activation of cytotoxic T lymphocytes (<em>in v…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | GLP - 2 (1 - 33) (human) |
| CAS NO. | 223460 - 79 - 5 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₆₅H₂₅₄N₄₄O₅₅S |
| Molecular Weight | 5040.74g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in water or phosphate - buffered |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | GLP - 2 (1 - 33) (human) has significant biological activity. It is known to play a key role in promoting intestinal growth, enhancing intestinal epithelial cell proliferation, and increasing intestinal absorption capacity. In addition, it can modulate the immune response within the gut, protecting the intestinal mucosa from damage and inflammation. |
| Storage Conditions | To maintain the stability and integrity of GLP - 2 (1 - 33) (human), it should be stored at - 20°C or below in a dry environment. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Stimulates cytotoxic T lymphocytes (CTLs) via major histocompatibility complex (MHC) class I presentation.
Enhances antigen-specific immune responses against melanoma cells expressing gp100.
Facilitates precise targeting of tumor-associated antigens for immunotherapy applications.
2.PRODUCT INDICATIONS
Research Use Only: Intended for preclinical studies on melanoma immunotherapy.
Cell-Based Assays: Suitable for evaluating T-cell activation and antitumor activity in vitro.
Therapeutic Development: Supports the design of gp100-based vaccines or adoptive cell therapies.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical Studies: Demonstrated potent CTL proliferation and cytokine release in melanoma models.
Functional Validation: Proven efficacy in enhancing tumor cell lysis viaMHC-restricted pathways.
Research Applications: Enables validation of gp100-targeted immunotherapies in benchtop experiments.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
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Global Technology Co., Ltd.
