Glucagon – Like Peptide 1 (7 – 37)
<p>Glucagon-Like Peptide 1 (7-37) is a high-purity bioactive peptide with the molecular formula <strong>C₁₅₁H₂₂<span style="font-size: 10px;">6</span>N₄₀O₄<span style="font-size: 10px;">6 </span></strong>and a molecular weight of<strong> 3337.73</strong><strong>g/mol</strong>. It is a key incretin hormone used in diabetes research, metabolic studies, and therapeutic development.<br/></p>
About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Glucagon-Like Peptide 1 (7-37), GLP-1 (7-37) |
| CAS NO. | |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C151H226N40O46 |
| Molecular Weight | 3337.73g/mol |
| Amino Acid Sequence | H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH (HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG) |
| Purity (RP-HPLC) | ≥95.0% |
| Solubility | Soluble in water (up to 1 mg/mL) |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Potent insulinotropic hormone that stimulates glucose-dependent insulin secretion, reduces glucagon release, and slows gastric emptying. Used in diabetes research and incretin-based therapeutic development. |
| Storage Conditions | Store at –20°C, protected from light and moisture. For long-term storage, recommend –80°C. |
| Stock Location | Stock in USA |
| MOQ | 10mg |
1.MECHANISM OF ACTION
This peptide activates the GLP-1 receptor on pancreatic β‑cells, stimulating adenylate cyclase and elevating intracellular cAMP. This results in glucose-dependent insulin secretion, suppression of glucagon release, delayed gastric emptying, and promotion of β‑cell proliferation and survival.
2.PRODUCT INDICATIONS
Glucagon-Like Peptide 1 (7-37) is widely used in studies of type‑2 diabetes, obesity, and metabolic syndrome. It serves as a reference standard in drug discovery, diagnostic assay development, and preclinical evaluation of GLP‑1‑based therapeutics.
3.CLINICAL EFFICACY OF PRODUCT
Clinical and preclinical data demonstrate that Glucagon-Like Peptide 1 (7-37) effectively improves glycemic control, enhances insulin sensitivity, reduces body weight, and protects pancreatic β‑cell function, supporting its role as a foundational molecule for incretin‑based therapies.
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Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
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