Chemicals

GLP-1 (7-36) amide (chicken, common turkey) CAS NO.1802078-26-7

<p>GLP-1 (7-36) amide (chicken, common turkey) is a high-purity synthetic peptide representing the active form of avian glucagon-like peptide-1, available for both chicken and common turkey species. This 30-amino acid peptide (C-terminal amide form) is specifically designed for avian metabolic research, featuring species-specific sequences that ensure physiological relevance in poultry studies. As a potent GLP-1 rec…

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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
GLP-1 (7-36) amide (chicken, common turkey)
CAS NO.
1802078-26-7
Appearance
White to off-white lyophilized powder
Molecular Formula
C149H224N40O47
Molecular Weight
3327.69 g/mol 
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in water, acetic acid (0.1%), PBS (pH 7-8)

Endotoxin< 1.0 EU/mg
Biological Activity
Avian glucagon-like peptide-1 (AGLP-1) is a GLP-1 receptor agonist; it promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and participates in the regulation of glucose homeostasis in birds.
Storage Conditions
Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

GLP-1 (7-36) amide (chicken, common turkey) binds specifically to avian GLP-1 receptors (GLP-1R) expressed on pancreatic beta cells and other target tissues. This binding activates G-protein coupled signaling pathways, primarily increasing intracellular cAMP levels and activating protein kinase A (PKA). Downstream effects include potent stimulation of glucose-dependent insulin secretion, inhibition of glucagon release, delayed gastric emptying, and promotion of satiety. The C-terminal amidation enhances peptide stability and receptor binding affinity. Importantly, this peptide exhibits species specificity for avian GLP-1 receptors, making it particularly valuable for poultry metabolic research and studies requiring species-matched ligands.


2.PRODUCT INDICATIONS

Avian Metabolic Research: Investigation of glucose homeostasis, insulin secretion, and incretin effects in chicken and turkey models

Comparative Endocrinology: Study of species-specific differences in GLP-1 signaling between avian and mammalian systems
Poultry Physiology: Research on appetite regulation, feed efficiency, and metabolic disorders in poultry
Receptor Pharmacology: Evaluation of avian GLP-1 receptor binding kinetics and signal transduction mechanisms
Preclinical Development: Assessment of GLP-1-based therapies for avian metabolic diseases
Species-Specific Studies: Research requiring avian-derived peptides for physiological relevance in bird models


3.CLINICAL EFFICACY OF PRODUCT

Species Coverage: Available for both chicken and common turkey, enabling comparative avian research
High Purity: ≥95% by RP-HPLC with mass spectrometry confirmation of species-specific sequences
Sequence Accuracy: Each species variant verified for correct amino acid sequence and C-terminal amidation
Biological Activity: Validated for stimulating insulin secretion in avian cell systems and receptor binding assays
Research Reproducibility: Consistent performance in metabolic studies and species comparison experiments
Quality Documentation: Certificate of Analysis provided for each batch with purity, mass spec, and species identification
Technical Support: Access to species-specific application guidance and experimental design consultation


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.