GLP-1 (7-36) amide (chicken, common turkey) CAS NO.1802078-26-7
<p>GLP-1 (7-36) amide (chicken, common turkey) is a high-purity synthetic peptide representing the active form of avian glucagon-like peptide-1, available for both chicken and common turkey species. This 30-amino acid peptide (C-terminal amide form) is specifically designed for avian metabolic research, featuring species-specific sequences that ensure physiological relevance in poultry studies. As a potent GLP-1 rec…
About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | GLP-1 (7-36) amide (chicken, common turkey) |
| CAS NO. | 1802078-26-7 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C149H224N40O47 |
| Molecular Weight | 3327.69 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water, acetic acid (0.1%), PBS (pH 7-8) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Avian glucagon-like peptide-1 (AGLP-1) is a GLP-1 receptor agonist; it promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and participates in the regulation of glucose homeostasis in birds. |
| Storage Conditions | Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
GLP-1 (7-36) amide (chicken, common turkey) binds specifically to avian GLP-1 receptors (GLP-1R) expressed on pancreatic beta cells and other target tissues. This binding activates G-protein coupled signaling pathways, primarily increasing intracellular cAMP levels and activating protein kinase A (PKA). Downstream effects include potent stimulation of glucose-dependent insulin secretion, inhibition of glucagon release, delayed gastric emptying, and promotion of satiety. The C-terminal amidation enhances peptide stability and receptor binding affinity. Importantly, this peptide exhibits species specificity for avian GLP-1 receptors, making it particularly valuable for poultry metabolic research and studies requiring species-matched ligands.
2.PRODUCT INDICATIONS
3.CLINICAL EFFICACY OF PRODUCT
4.DELIVERY & SHIPPING
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