[Tyr22] Gastric Inhibitory Peptide (22-42), human

<p>[Tyr22] Gastric Inhibitory Peptide (22-42), human is a synthetic peptide fragment derived from the C-terminal region of human Gastric Inhibitory Polypeptide (GIP), featuring a tyrosine modification at position 22. This 21-amino acid peptide is specifically designed for structural and functional studies of GIP receptor interactions, antibody epitope mapping, and metabolic research applications. The tyrosine modifi…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Tyr22] Gastric Inhibitory Peptide (22-42), human
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₁₀H₁₄₀N₂₀O₂₀S (estimated value, requires precise calculation)
Molecular Weight	~ 2500 Da (Calculated value, needs confirmation)
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, dilute acetic acid, DMSO
Endotoxin	< 1.0 EU/mg
Biological Activity	A site-directed Tyr-modified derivative of the C-terminal fragment (positions 22-42) of human gastric inhibitory peptide (GIP); this fragment may be involved in the binding and signal regulation of the GIP receptor and is often used for receptor structure-function studies, antibody development, or as a detection standard.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

[Tyr22] GIP (22-42), human represents a site-specifically modified fragment of the human GIP hormone. The tyrosine residue at position 22 may serve as a functional handle for conjugation, labeling, or detection purposes, while potentially maintaining or altering the peptide's interaction with GIP receptors or antibodies. This peptide can be used to study the role of specific amino acid residues in receptor binding affinity, signal transduction, or antibody recognition. The modification allows researchers to investigate how single amino acid changes affect biological activity, making it valuable for structure-function relationship studies, epitope mapping, and the development of modified peptides for research or diagnostic applications.

2.PRODUCT INDICATIONS

Structure-Function Studies: Investigation of specific amino acid residues in GIP receptor binding and signaling

Epitope Mapping: Identification of antibody binding sites and development of specific antibodies

Receptor Pharmacology: Study of GIP receptor interactions and ligand-receptor specificity

Metabolic Research: Exploration of GIP's role in glucose homeostasis and incretin physiology

Diagnostic Development: Use as a standard or tracer in immunoassays for GIP detection

Peptide Engineering: Research on modified peptides for enhanced stability or activity

3.CLINICAL EFFICACY OF PRODUCT

High Purity: ≥95% by RP-HPLC with mass spectrometry confirmation of sequence and modification

Site-Specific Modification: Precise tyrosine incorporation at position 22, verified by analytical methods

Research Reliability: Consistent batch-to-batch performance in receptor binding and antibody studies

Analytical Utility: Validated for use in structural biology, epitope mapping, and diagnostic assay development

Quality Documentation: Each batch includes Certificate of Analysis with purity, mass spec, and amino acid analysis data

Technical Support: Access to expert consultation on peptide applications and experimental design

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.