GRF, porcine

<p>GRF, porcine (Growth Hormone-Releasing Factor, porcine) is a high-purity synthetic peptide corresponding to the 44-amino acid sequence of porcine growth hormone-releasing hormone (GHRH). This bioactive peptide functions as a potent and specific agonist for GHRH receptors, stimulating growth hormone secretion from pituitary somatotrophs. With HPLC-verified purity and comprehensive analytical documentation, it prov…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	GRF, porcine (Growth Hormone-Releasing Factor, porcine)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C219H365N73O66S
Molecular Weight	5108.86 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, acetic acid (0.1%), and DMSO; may require gentle vortexing for complete dissolution
Endotoxin	< 1.0 EU/mg
Biological Activity	Growth hormone-releasing hormone (GHRH) agonist; stimulates growth hormone secretion from anterior pituitary somatotrophs via activation of GHRH receptor.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

GRF, porcine binds with high affinity to GHRH receptors on pituitary somatotroph cells, activating G-protein coupled signaling pathways. This binding stimulates adenylate cyclase activity, increasing intracellular cAMP levels and activating protein kinase A (PKA). The downstream effects include phosphorylation of transcription factors (such as CREB), enhanced growth hormone gene expression, and stimulation of growth hormone synthesis and secretion. The peptide exhibits species specificity for porcine GHRH receptors, making it particularly valuable for porcine-based research models of growth, metabolism, and agricultural applications.

2.PRODUCT INDICATIONS

Porcine Endocrine Research: Investigation of growth hormone regulation, pituitary function, and growth axis signaling in swine models

Agricultural Science Studies: Research on growth hormone's role in growth promotion, feed efficiency, and body composition in pigs

Metabolic Studies: Investigation of metabolic regulation and energy homeostasis in porcine systems

Animal Model Development: Use in porcine models of growth hormone deficiency and metabolic disorders

Drug Discovery: Screening for GHRH receptor agonists or antagonists for veterinary or agricultural applications

Receptor Pharmacology: Study of porcine GHRH receptor binding, signal transduction, and species specificity

3.CLINICAL EFFICACY OF PRODUCT

Validated Bioactivity: Demonstrated potent stimulation of growth hormone secretion in porcine pituitary cells and in vivo models

High Purity: ≥95% by RP-HPLC with mass spectrometry confirmation of sequence and C-terminal amidation

Species Specificity: Optimized for porcine GHRH receptors, ensuring reliable results in porcine-based research

Research Reproducibility: Consistent performance in growth hormone release assays, receptor binding studies, and animal experiments

Quality Assurance: Produced under controlled conditions with low endotoxin levels for research applications

Translational Relevance: Supports research on growth promotion, metabolic regulation, and endocrine function in swine models

Documentation: Each batch includes Certificate of Analysis with purity, mass spec, and biological activity data

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.