C-terminal Proghrelin Isoform Peptide, mouse

<p>C-terminal Proghrelin Isoform Peptide, mouse is a high-purity synthetic peptide corresponding to the C-terminal region of mouse proghrelin, a precursor protein for the appetite-regulating hormone ghrelin. This peptide is designed for advanced research in metabolic regulation, energy homeostasis, and neuroendocrine signaling. With HPLC-verified purity and comprehensive analytical documentation, it provides researc…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	C-terminal Proghrelin Isoform Peptide, mouse
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C50H86N22O17
Molecular Weight	4231.6 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, acetic acid (0.1%), DMSO; gentle solubilization may be required.
Endotoxin
Biological Activity	The C-terminal isoform fragment of proghrelin in the forestomach; it may be involved in the regulation of energy metabolism, appetite control and growth hormone secretion, and is a tool peptide for studying the non-classical function and signal transduction of the ghrelin system.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

C-terminal Proghrelin Isoform Peptide, mouse may function through multiple pathways, including potential interactions with G-protein coupled receptors such as GPR39 (obestatin receptor) or other yet-to-be-identified receptors. It may modulate intracellular signaling cascades involving cAMP, calcium mobilization, or MAPK pathways, leading to effects on appetite regulation, energy expenditure, and hormone secretion. Unlike ghrelin, which acts through GHSR-1a, this C-terminal fragment represents a distinct bioactive component of the proghrelin system with potentially unique physiological roles in metabolic homeostasis.

2.PRODUCT INDICATIONS

Metabolic Research: Investigation of appetite regulation, energy balance, and obesity-related mechanisms

Endocrine Studies: Research on growth hormone secretion, insulin sensitivity, and metabolic hormone interactions

Neuroscience Research: Exploration of central nervous system effects on feeding behavior and neuroendocrine regulation

Drug Discovery: Screening for novel modulators of metabolic pathways and appetite control

Preclinical Models: Use in mouse-based studies of metabolic disorders, diabetes, and cachexia

Receptor Pharmacology: Study of potential receptor interactions and signaling mechanisms

3.CLINICAL EFFICACY OF PRODUCT

Research Reliability: High purity (≥95% by HPLC) and validated sequence ensure reproducible experimental outcomes

Functional Relevance: Supports studies on proghrelin-derived peptide biology and metabolic regulation

Versatile Applications: Suitable for cell-based assays, receptor binding studies, and animal models of metabolism

Quality Assurance: Produced under controlled conditions with low endotoxin levels for research use

Translational Potential: Facilitates understanding of metabolic disorders and potential therapeutic targets

Documentation: Each batch includes analytical data with purity, mass spectrometry, and quality control information

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.