Gastrin-1, human ( Gastrin17) CAS NO.10047-33-3

Gastrin-1, human (Gastrin 17) (CAS No. 10047-33-3) is a high-purity peptide with the molecular formula C₁₁₀H₁₃₀N₂₂O₂₀S₂ and a molecular weight of 2098.22g/mol. It is widely used in gastrointestinal research and diagnostic studies for its role in gastric acid secretion and mucosal growth regulation.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Gastrin-1, human (Gastrin 17)
CAS NO.	10047-33-3
Appearance	White to off-white lyophilized powder
Molecular Formula	C97H125N20O31S
Molecular Weight	2098.22g/mol
Amino Acid Sequence	Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH₂ (Pyr = pyroglutamic acid)
Purity (RP-HPLC)	≥95.0% (can be customized to ≥98.0%)
Solubility	Soluble in water, dilute acetic acid solution, and aqueous buffers
Endotoxin	<1.0 eu="">
Biological Activity	Stimulates gastric acid secretion and mucosal cell growth; used in gastrointestinal physiology, cancer, and ulcer research.
Storage Conditions	Store at –20°C, protected from light and moisture.
Stock Location	Stock in USA
MOQ	1mg

1.MECHANISM OF ACTION

Gastrin-1, human (Gastrin 17) functions by binding to cholecystokinin-2 receptors (CCK2R) on gastric parietal cells, stimulating the release of gastric acid through intracellular calcium and protein kinase signaling pathways. It also promotes the growth and proliferation of gastric mucosal cells, contributing to the maintenance of gastrointestinal integrity.

2.PRODUCT INDICATIONS

This peptide is used in research focused on gastric physiology, peptic ulcer disease, gastrointestinal cancers, and diagnostic assays for gastrin-related disorders. It is also applied in studies of hormone secretion, cell proliferation, and the development of therapeutic agents targeting acid-related gastrointestinal conditions.

3.CLINICAL EFFICACY OF PRODUCT

Clinical and preclinical studies have demonstrated that Gastrin-1, human (Gastrin 17) effectively stimulates gastric acid secretion and supports mucosal repair in experimental models. Its role as a biomarker and therapeutic target in conditions like Zollinger-Ellison syndrome and gastric adenocarcinoma underscores its relevance in translational gastrointestinal research.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.