Gastrin, chicken

Gastrin, Chicken is a bioactive peptide hormone specifically derived from avian (chicken) sources, playing a crucial role in the regulation of gastric acid secretion and gastrointestinal functions in avian species. This peptide exists in multiple molecular forms, with the predominant active form typically being a 17-amino acid peptide (G-17) that shares structural homology with mammalian gastrins but contains specie…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Gastrin, Chicken
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C190H265N47O51S
Molecular Weight	4055.58 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, PBS (pH 7.0-7.5), dilute acetic acid
Endotoxin	< 1.0 EU/mg
Biological Activity	Functional fragments of fibronectin type III junctions; involved in cell adhesion, migration, signal transduction, and tissue repair; commonly used in integrin binding, cell-matrix interaction, wound healing, and tumor metastasis research.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C or -80°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Chicken Gastrin exerts its physiological effects by binding to cholecystokinin-B/gastrin receptors (CCK-BR) on gastric parietal cells and enterochromaffin-like (ECL) cells. This receptor is a G-protein coupled receptor that primarily activates the Gq/11 signaling pathway. Upon binding, it triggers phospholipase C (PLC) activation, leading to increased inositol trisphosphate (IP3) and diagoglycerol (DAG) production.

2.PRODUCT INDICATIONS

Comparative Endocrinology Studies: Investigating evolutionary differences in gastrointestinal hormone structure and function between avian and mammalian species
Avian Veterinary Research: Studying gastric physiology, digestive disorders, and nutritional absorption in poultry and avian species
Species-Specific Receptor Studies: Characterizing CCK-B/gastrin receptor binding affinity, specificity, and signaling in avian tissues
Developmental Biology: Examining the role of gastrin in gastrointestinal tract development and maturation in avian embryos
Agricultural Science Research: Optimizing feed efficiency and growth performance in poultry through hormonal regulation studies
Pharmacological Screening: Testing gastrin receptor agonists/antagonists for potential veterinary applications
Molecular Evolution Research: Analyzing peptide hormone evolution across vertebrate species

3.CLINICAL EFFICACY OF PRODUCT

Research Validation: Studies demonstrate that chicken gastrin effectively stimulates gastric acid secretion in avian gastric preparations and shows cross-reactivity in some mammalian assay systems due to receptor homology

Veterinary Relevance: Research using chicken gastrin contributes to understanding digestive disorders in poultry, potentially informing management strategies for conditions like gastric hypersecretion or ulcers in commercial flocks

Diagnostic Potential: In research settings, it may be used to develop species-specific assays for assessing gastric function in avian veterinary medicine

Therapeutic Gap: No approved therapeutic products based on chicken gastrin exist for clinical veterinary practice; its primary value remains in basic physiological research

Translational Limitations: Significant sequence differences from mammalian gastrins prevent direct therapeutic substitution, though mechanistic insights may inform broader gastrointestinal research

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.