Galanin, porcine CAS NO.88813-36-9

Galanin, porcine (CAS 88813-36-9) is a high-purity, 29-amino acid neuropeptide extracted and synthesized from porcine tissue, widely recognized for its critical role in modulating neurotransmission, endocrine function, and metabolic regulation. This bioactive peptide, characterized by its C-terminal amidation, exhibits high specificity for galanin receptors (GalR1, GalR2, GalR3) in both the central and peripheral ne…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Galanin, porcine
CAS NO.	88813-36-9
Appearance	White to off-white lyophilized powder
Molecular Formula	C146H213N43O40
Molecular Weight	3210.55 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, acetic acid (0.1%), DMSO; may require gentle vortexing or sonication
Endotoxin	< 1.0 EU/mg
Biological Activity	Neuropeptide; inhibits insulin secretion, modulates neurotransmitter release, and regulates feeding behavior, nociception, and memory.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Galanin, porcine functions primarily by binding to and activating G-protein coupled galanin receptors (GalR1, GalR2, and GalR3). This interaction modulates intracellular signaling pathways, including inhibition of adenylate cyclase and regulation of ion channels, leading to reduced neurotransmitter release (such as acetylcholine, norepinephrine, and glutamate), altered neuronal excitability, and downstream effects on hormone secretion, feeding behavior, and nociception. Its action is highly conserved across species, making it a reliable tool for translational neuroscience and endocrine research.

2.PRODUCT INDICATIONS

Neuroscience Research: Investigation of synaptic transmission, learning and memory, anxiety, depression, and neurodegenerative diseases.

Endocrine Studies: Exploration of insulin secretion, growth hormone regulation, and metabolic disorders.

Pain and Nociception: Research on galanin’s role in modulating pain pathways and inflammatory responses.

Feeding Behavior and Obesity: Studies on appetite regulation, energy homeostasis, and related metabolic syndromes.

Drug Discovery: Screening and development of galanin receptor-targeted therapeutics for neurological and endocrine disorders.

3.CLINICAL EFFICACY OF PRODUCT

Validated Biological Activity: Demonstrated potent receptor binding and functional modulation in cell-based and animal models.

High Purity: ≥95% by RP-HPLC with confirmed amino acid sequence and molecular weight via mass spectrometry.

Reproducible Research Outcomes: Consistent performance in neurotransmitter release assays, hormone secretion studies, and behavioral tests.

Translational Relevance: Supports preclinical studies on epilepsy, Alzheimer’s disease, diabetes, and chronic pain.

Quality Assurance: Produced under GLP-like conditions with low endotoxin levels suitable for in vitro and in vivo applications.

Regulatory Compliance: Suitable for use in FDA- and EMA-relevant research and drug development pipelines.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.