Fibrinopeptide B, Bovine

Fibrinopeptide B, Bovine is a 24-amino-acid peptide derived from the β-chain of bovine fibrinogen, with the molecular formula C₁₀₁H₁₅₄N₃₀O₃₆ and molecular weight 2364.53 g/mol. As a key intermediate in bovine blood coagulation, it plays a critical role in fibrin polymerization and clot formation, making it indispensable for veterinary hemostasis research and comparative coagulation studies.

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Fibrinopeptide B, Bovine
CAS NO.	\
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₀₁H₁₅₄N₃₀O₃₆
Molecular Weight	2364.53 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in water (pH 4.0–7.0) or 0.1 M acetic acid; slightly soluble in DMSO (≤5 mg/mL)
Endotoxin	< 1.0 EU/mg
Biological Activity	Released from bovine fibrinogen β-chain during thrombin cleavage; regulates fibrin polymerization and clot structure. Used to study comparative coagulation mechanisms (bovine vs. human) and validate fibrinogen assays.
Storage Conditions	Store at -20°C in a desiccated, light-protected container; avoid repeated freeze-thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Fibrinopeptide B, Bovine is released from bovine fibrinogen during thrombin-mediated cleavage (at Arg²⁰-Gly²¹ bond). Its primary functions include:

Initiating Fibrin Polymerization: Removal of Fibrinopeptide B exposes polymerization sites on fibrinogen, enabling lateral aggregation of fibrin monomers into protofibrils.

Modulating Clot Structure: Regulates the density and stability of fibrin clots by influencing protofibril branching and cross-linking.

Species-Specific Coagulation Marker: Serves as a biomarker for bovine thrombotic activity, correlating with clot formation rates in veterinary contexts.

2.PRODUCT INDICATIONS

This peptide is widely used in:

Veterinary Hemostasis Research: Studying thrombin-fibrinogen interactions and fibrin assembly dynamics in cattle and other livestock.

Comparative Coagulation Studies: Analyzing species-specific differences between bovine and human fibrinogen/fibrin systems.

Assay Validation: Validating bovine fibrinogen-dependent diagnostic tools (e.g., ELISA kits for veterinary DIC or thrombosis).

3.CLINICAL EFFICACY OF PRODUCT

Research Applications: In vitro studies confirm its role in accelerating bovine fibrin clot formation (2–3x faster polymerization vs. uncleaved fibrinogen).

Biomarker Utility: Plasma Fibrinopeptide B levels rise significantly during bovine thrombotic events, enabling early detection in veterinary practice.

Diagnostic Accuracy: ELISA-based assays using this peptide achieve high sensitivity/specificity for bovine DIC diagnosis in field trials.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.