Fibrinogen β-Chain (24-42)

Fibrinogen β-Chain (24-42) is a bioactive peptide fragment derived from the β-chain of fibrinogen, playing a vital role in coagulation, thrombosis, and cellular interaction studies. This synthetic peptide, with high purity and verified biological activity, serves as an essential research tool for investigating fibrinogen-mediated signaling pathways, platelet activation, and clot formation mechanisms. Available as a …

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Fibrinogen β-Chain (24-42)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₉₂H₂₈₉N₄₇O₆₁
Molecular Weight	4231.6 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, PBS (pH 7.0-7.5), dilute acetic acid; may require gentle sonication or mild acid for complete dissolution
Endotoxin	< 1.0 EU/mg
Biological Activity	Functional fragments of the fibrinogen β chain; involved in coagulation cascade reactions, platelet aggregation and inflammation regulation; often used to study its interaction with receptors such as integrins and selectins, and its role in thrombosis, wound repair and tumor metastasis.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C or -80°C; avoid repeated freeze-thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Fibrinogen β-Chain (24-42) functions by interacting with key receptors involved in coagulation and cellular adhesion, such as integrin αIIbβ3 (GPIIb/IIIa) and other fibrinogen-binding proteins. This interaction facilitates platelet aggregation, stabilizes fibrin clot formation, and modulates inflammatory responses. The peptide’s sequence corresponds to a functional domain critical for fibrin polymerization and cross-linking, influencing thrombus stability and resolution. Its role in signaling pathways also extends to endothelial and immune cell activation, contributing to vascular homeostasis and tissue repair processes.

2.PRODUCT INDICATIONS

Coagulation Research: Studies on fibrinogen function, platelet aggregation, and thrombus formation
Vascular Biology: Investigation of endothelial cell activation, vascular permeability, and angiogenesis
Inflammation Studies: Research on fibrinogen-mediated inflammatory signaling and immune cell recruitment
Drug Discovery: Screening for antithrombotic, anti-inflammatory, or antifibrotic therapeutic agents
Disease Modeling: Tools for studying atherosclerosis, deep vein thrombosis, stroke, and other fibrinogen-related disorders

3.CLINICAL EFFICACY OF PRODUCT

Research Reliability: Consistent performance in platelet aggregation assays, clot formation studies, and receptor binding experiments
Biological Relevance: Validated role in mimicking native fibrinogen function in preclinical models
High Purity: ≥95% HPLC purity with comprehensive characterization (mass spec, amino acid analysis)
Experimental Versatility: Suitable for in vitro and in vivo studies of coagulation, inflammation, and vascular pathology
Technical Support: Detailed protocols and activity data provided for seamless integration into research workflows
Translational Potential: Aids in identifying novel biomarkers and therapeutic targets for thrombotic and inflammatory diseases

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.