ARA290 (Cibinetide) CAS NO.1208243-50-8

ARA290 (Cibinetide), CAS NO. 1208243 - 50 - 8, is a synthetic peptide with the molecular formula C51H84N16O21 and a molecular weight of approximately 1243.46 g/mol. It is a promising compound in the field of biomedical research due to its unique biological activities.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	ARA290 (Cibinetide)
CAS NO.	1208243 - 50 - 8
Appearance	White to off-white lyophilized powder
Molecular Formula	C51H84N16O21
Molecular Weight	1257.31 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in water
Endotoxin	< 1.0 EU/mg
Biological Activity	ARA290 exhibits cytoprotective, anti - inflammatory, and tissue - regenerative properties. In pre - clinical and some clinical studies, it has demonstrated potential in treating various diseases and conditions related to tissue damage, inflammation, and oxidative stress
Storage Conditions	Store at - 20°C in a dry and dark environment. Avoid repeated freeze - thaw cycles to maintain product stability.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

ARA290 functions by binding to the erythropoietin receptor (EPOR) and its associated signaling complexes. This binding activates downstream signaling pathways, including the JAK2 - STAT5 pathway. These pathways play crucial roles in cell survival, proliferation, and differentiation. By modulating these signaling cascades, ARA290 exerts its cytoprotective, anti - inflammatory, and tissue - regenerative effects. It can protect cells from various forms of stress, such as oxidative stress and ischemia - reperfusion injury, and also reduce the production of pro - inflammatory cytokines.

2.PRODUCT INDICATIONS

Renal Diseases: Investigated for reducing inflammation and promoting tissue repair in acute/chronic kidney injury.

Cardiovascular Disorders: Potential use in myocardial infarction and heart failure to protect cardiac cells, improve contractility, and reduce post-infarction scar formation.

Neurological Conditions: Explored for aiding neural tissue recovery and mitigating neuroinflammation in disorders like stroke or traumatic brain injury.

Metabolic Diseases: Studied for alleviating oxidative stress and tissue damage in metabolic syndrome-related complications.

3.CLINICAL EFFICACY OF PRODUCT

In renal injury models: Reduced kidney damage progression, improved glomerular filtration rate (GFR), and decreased inflammatory cell infiltration.

In cardiovascular models: Enhanced cardiac function and reduced infarct size after myocardial infarction.

In neurological models: Promoted neuronal survival and reduced neuroinflammatory markers

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

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