Ikdoin CAS NO. 96702-03-3

Ikdoin (CAS NO. 96702-03-3), also known as Ectoin, is a natural amino acid derivative first isolated from halophilic bacteria. Celebrated as a "cellular protector" and "molecular shield," it boasts exceptional cell-protective, moisturizing, and repairing properties.  <div style="color: rgb(31, 35, 41); font-v…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Lkdoin
CAS NO.	96702-03-3
Appearance	White to off-white fine powder
Molecular Formula	C₁₁H₁₄N₂O₃S
Molecular Weight	254.306 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in DMSO (≥ 50 mg/mL) Soluble in methanol (≥ 20 mg/mL) Slightly soluble in water (≈ 1-2 mg/mL at 25°C)
Endotoxin	< 1.0 EU/mg
Biological Activity	Ikdoin acts as a selective agonist for the G-protein coupled receptor (GPCR) GPR119, stimulating insulin secretion in a glucose-dependent manner and enhancing glucagon-like peptide-1 (GLP-1) release, making it a key research tool for metabolic disease studies.
Storage Conditions	Short-term (1-3 months): Store at 4°C in a sealed container, protected from light and moisture. Long-term (12+ months): Store at -20°C or -80°C in a desiccated environment; avoid repeated freeze-thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Hydration Shell Formation: Ikdoin exhibits strong water-binding capacity, forming a stable, ordered "hydration shell" around cells, enzymes, and proteins to lock in moisture and prevent transdermal water loss.

Structural Stabilization: It stabilizes cell membranes and protein structures, shielding biological molecules from external stressors like UV radiation, extreme temperatures, and pollutants.

Anti-Inflammatory Regulation: It inhibits inflammatory signaling pathways (e.g., NF-KB), reducing skin sensitivity and irritation while protecting epidermal immune cells (Langerhans cells) from UV-induced damage.

Osmotic Balance Maintenance: As an osmolyte, it helps cells maintain osmotic equilibrium, resisting dehydration and environmental stress.

2.PRODUCT INDICATIONS

Cosmetics: Ideal for moisturizers, anti-aging serums, after-sun care, sensitive skin products, and post-procedure (laser/peel) repair formulations.

Pharmaceuticals: Used in topical treatments for atopic dermatitis, eczema, and allergic skin conditions; also applied in nasal sprays for allergic rhinitis and eye drops for ocular inflammation.

Healthcare Products: Added to supplements and personal care items targeting skin barrier repair and environmental stress protection.

Specialty Formulations: Enhances stability of active ingredients (peptides, enzymes) in high-performance skincare and medical products.

3.CLINICAL EFFICACY OF PRODUCT

Long-Lasting Hydration: Clinical data shows Ikdoin reduces transepidermal water loss (TEWL) significantly, maintaining skin moisture for up to 7 days without repeated use; 0.5%-1.0% formulations sustain 60% skin hydration 19 days post-application.

UV Protection & Repair: 0.5% Ikdoin achieves 100% protection of epidermal melanocytes from UV damage, preventing photoaging and DNA breakage.

Skin Barrier Restoration: Effectively repairs damaged skin barriers, improving elasticity and reducing roughness; accelerates skin regeneration in post-inflammatory and post-procedure scenarios.

Anti-Inflammatory Efficacy: Proven to relieve redness, stinging, and itching associated with sensitive skin and atopic dermatitis, serving as a safe alternative to corticosteroids.

Anti-Pollution Performance: Clinically validated to shield skin and respiratory tracts from pollutant-induced damage, supporting prevention of conditions like COPD and asthma.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.